I don't see how. Naoki Urasawa uses his medium as brilliantly and intimately as Alan Moore. Most truly great comics and manga flounder in other media, though Japan is more willing to make movies that are big long ads for the comics. That's all I thought the 20th Century Boys movies were, frankly.
Persepolis is very faithful to the original work but cuts and streamlines the original work considerably in the interests of maintaining a better running time. The stuff that's cut simplifies the experience, so there's still value in reading the original comics (which cover a longer span of time in the artist's life).