Well TDK still just isn't for everyone, its just not one of those timeless movies that just about anyone can watch and love. Yes TDK was timeless but its still has a target range narrower than Benjamin Button for example, just not everyone can get into TDK. That being said I think TDK was more deserving of the best picture spot than The Reader, but so are a few other movies. I dunno I just didn't feel that amazing film feel from The Reader, but they feel very strong about The Reader for some reason so lets see.
Anyway I would like for Milk or Frost/Nixon to win best picture but its most likely gonna be Slumdog Millionaire.
Milk is probably going to walk away with Best Original Screenplay while Benjamin Button takes Best Adapted Screenplay. Then again maybe Benjamin Button wont with its controversy behind the script (ala its written by the same guy that wrote Forrest Gump and it shows great parallels with Forrest Gump).
Sean Penn (Milk) is most likely going to take the best lead actor and Kate Winslet (The Reader) is probably going to take best lead actress.