Hey speaking of Otto guess what is having it's thirty-second issue in August. That's right Superior Spider-Man. It seems that his disappearance in issue 19 was an out to have more adventures. It seems that he was thrown into the World of Tomorrow, into the year 2099. Say what you will about the series as a whole this is actually a rather smart move. Everyone knew Peter was going to be back to Amazing at some point, so they came up with this if the Otto-Spidey proved popular. Plus Otto would make a better hero in the year 2099. Not only is he free of baggage, but this is a world so corrupt that Victor Von Doom can be a hero.
Also this makes bringing Otto back as either Spidey or Doc Ock really easy. He is now just a future technology macguffin away from being alive again.