I know people are lenient towards their first real anime, but I was blown away when I saw this. To me, this was my first real anime, and I loved every minute of it.
The first half was heartbreaking, and the latter half was epic, in both storytelling and its litteral size (LOL BREAKING HOLES IN THE UNIVERSE). It's definitely a show you should watch at least once in your life. The characters (at least the main three heroes, and Viral) will stay with you forever.
PIERCE THE HEAVENS AND KICK REASON TO THE CURB!
Keith, DVDs of Gurren Lagann won't be released until sometime this month or so. And if they're released already, it's only the first or second volume that's out. Hardly the whole series yet.
As for the second half, I loved it. It took the show in a complete direction, similar to Lost Galaxy's second half. But it was refreshing to see how much they've grown, and what each of them were willing to do to fulfill their destiny. It was great.
...except Simon's ending kinda blew. >_>