Spider-Man pointing meme used to promote the DVD release of Spiderman: No Way Home!
Spider-Man pointing meme came from a 1967 episode of the Spider-Man (1967 Animated TV series). In this Episode, Chameleon is disguised as Spider-Man because he wants to set him up. That episode leads to the imposter and real one pointing at each other. Who would have thought that a cartoon episode would resurface to a new generation? Back in 2011, Someone uploaded this picture as a template on Sharenator.com. This screencap is so captionable that people have used it to make memes until now.